Ramin Faghih,Achim Moeller,Michael Ochse,Frauke Pohlki,Martin Schmidt,Kevin Sippy,Sean Turner,Elizabeth Louise Van Der Kam
申请号：
US15793711
公开号：
US10155770B2
申请日:
2017.10.25
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Compounds of formula (I)and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, L1 and G1 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by positive allosteric modulation of the γ-aminobutyric acid B (GABA-B) receptor. Methods for making the compounds are described. Also described are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
