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SUBSTITUTED ISOXAZOLOPYRIDAZINONES AND ISOTHIAZOLOPYRIDAZINONES AND METHODS OF USE
专利权人:
AbbVie Inc.;AbbVie Deutschland GmbH &; Co. KG
发明人:
Jürgen DINGES,Achim MOELLER,Michael OCHSE,Martin SCHMIDT,Michael SCHULZ,Sean TURNER,Elizabeth Louise VAN DER KAM,Anil VASUDEVAN
申请号:
US16409323
公开号:
US20190367531A1
申请日:
2019.05.10
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Compounds of formula (I)and pharmaceutically acceptable salts thereof, wherein R1, R2 and R3 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by positive allosteric modulation of the γ-aminobutyric acid B (GABA-B) receptor. Methods for making the compounds are described. Also described are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
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