STEVENS INSTITUTE OF TECHNOLOGY;HACKENSACK UNIVERSITY MEDICAL CENTER
发明人:
ZILBERBERG, JENNY,LEE, WOO,KORNGOLD, ROBERT
申请号:
CA2972846
公开号:
CA2972846A1
申请日:
2016.01.08
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The described invention provides an ex vivo model of persistent T lymphocyte stimulation events encountered by circulating T lymphocytes at lymph node and tissue levels in vivo; a method for optimizing donor selection for allogeneic blood and marrow transplantation (BMT) therapy; and a method for minimizing risks and maximizing benefits of performing allogeneic blood and marrow transplantation (BMT) therapy in a recipient subject, wherein the recipient subject has a hematologic malignancy.