FIELD: medicine.SUBSTANCE: invention refers to medical equipment, namely syringes. A first object - a piston for the syringe comprising a retractable needle is designed to engage the needle and comprises a piston rod, an external portion of the piston, a control element and a displacement element. The rod, the external part of the piston and the control element are coupled for holding a released displacement element in an initially strained condition. The displacement element is released from the initially strained condition to retract the piston engaged with the needle. A second object - the syringe with the retracted needle, comprises a cylinder, the retracted needle and said piston. The piston is designed to engage with the needle thereby making it retracting after fluid delivery from the syringe. The third object - a released needle holding system attached to the syringe cylinder, comprises the retracted needle, a needle seal and a holding element. The needle comprises a body having a base engaged with the piston to provide retraction. The seal releasing the base is engaged with the piston. The holding element comprises a coupling surface joined to a coupling surface of an internal wall of the cylinder. The holding element initially holds the needle in a needle end of the cylinder until the needle is engaged with the piston to providing needle retraction. A fourth object - the syringe with the retracted needle comprises the cylinder, the piston and said released needle holding system. A fifth object - the pre-filled syringe with the retracted needle comprises a glass cylinder containing an internal wall and a bushing comprising a release ring the released needle holding system the piston engaged with a needle and blocking systems. Said system comprises a needle assembly which comprises the needle and the needle seal the holding element comprising the coupling surface joined to the coupling surface of the internal wall and a pullback element for needle release fr
