Sofie Jeanne Leopoldine Celen;Meri De Angelis;José Ignacio Andrés-Gil;Guy Maurits R. Bormans
发明人:
José Ignacio Andrés-Gil,Meri De Angelis,Guy Maurits R. Bormans,Sofie Jeanne Leopoldine Celen
申请号:
US13505157
公开号:
US08852554B2
申请日:
2010.10.27
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to novel, selective, radiolabelled PDE10 ligands which are useful for imaging and quantifying the PDE10A enzyme in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo.