METHODES DE TRAITEMENT D'AFFECTIONS PRURIGINEUSES MEDIEES PAR LES RECEPTEURS DE L'HISTAMINE H-4

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专利权人:

BRIDGE PHARMA; INC.

发明人:

ABERG, A. K. GUNNAR,CIOFALO, VINCENT B.

申请号：

CA2919078

公开号：

CA2919078A1

申请日:

2014.07.31

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

The methods disclosed herein relate to the treatment of histamine H-4 - related dermal disorders, by administering a histamine H-4 receptor inverse agonist that selectively accumulates at the biophases for the disorders, specifically RS-norketotifen or a pharmaceutically acceptable salt thereof. Potentiated antipruritic activity by simultaneous inhibition of histamine H-1 receptors and histamine H-4 receptors are described.

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