pharmaceutical composition, and methods for reducing plaque loading in a patient's retinal ganglion cell layer, for reducing the amount of plaque in a patient's retinal ganglion cell layer, for decreasing the total amount of soluble beta-amyloid in the patient layer of a patient's retinal ganglion to prevent, treat or alleviate the effects of an eye disease associated with pathological abnormalities / changes in visual system tissues, to diagnose a predisposition to an eye disease associated with pathological abnormalities / changes in system tissue to monitor for minimal residual ocular disea
Andrea Pfeifer,Andreas Muhs,Maria Pihlgren,Ryan Watts
申请号：
BRPI0818643
公开号：
BRPI0818643A2
申请日:
2008.10.03
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
The present invention provides novel methods and compositions comprising highly specific and highly effective antibodies that specifically recognize and bind to specific epitopes from a range of ²-amyloid proteins. The antibodies of the present invention are particularly useful for the treatment of ocular diseases associated with pathological abnormalities/changes in the tissues of the visual system, particularly those ocular diseases associated with amyloid-beta-related pathological abnormalities/changes in the tissues of the visual system.
