Bernard Luke Flynn,Jonathan B. Baell,Andrew J. Harvey,Jason Hugh Chaplin,Dharam Paul,Jorgen Alvar Mould
申请号:
US12444211
公开号:
US08309545B2
申请日:
2007.10.04
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to compounds useful in the modulation of potassium channel activity in cells, in particular the activity of Kv1.3 channels found in T cells. The invention also relates to the use of these compounds in the treatment or prevention of autoimmune and inflammatory diseases, including multiple sclerosis, pharmaceutical compositions containing these compounds and methods for their preparation.