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Aryl potassium channel blockers and uses thereof
专利权人:
Bernard Luke Flynn
发明人:
Bernard Luke Flynn,Jonathan Bayldon Baell,Jason Hugh Chaplin,Gurmit Singh Gill,Damian Wojciech Grobelny,Andrew John Harvey,Jorgen Alvar Mould,Dharam Paul
申请号:
US12681763
公开号:
US08202513B2
申请日:
2008.10.03
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to compounds useful in the modulation of potassium channel activity in cells, in particular the activity of Kv1.3 channels found in T cells. The invention also relates to the use of these compounds in the treatment or prevention of autoimmune and inflammatory diseases, including multiple sclerosis, pharmaceutical compositions containing these compounds and methods for their preparation.
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