LEE, SEUNG JAE,이승재,KIM, CHANG YOUN,김창연,LEE, HE JIN,이혜진
申请号:
KR1020110009291
公开号:
KR1020120088150A
申请日:
2011.01.31
申请国别(地区):
KR
年份:
2012
代理人:
摘要:
PURPOSE: A method for identifying a material having neuropathic disease treatment effect is provided to effectively identify the material using toll-like receptor 2.CONSTITUTION: A method for identifying a material having neuropathic disease treatment effect comprises: a step of contacting a material with toll-like receptor(TLR) 2 and a step of determining the effect of a material to TLR 2. TLR 2 has an amino acid sequence of sequence number 1. An essay for the effect of a material to TLR2 comprises a step of evaluating the reduction of binding between TLR 2 antibody and TLR 2. A kit for identifying the material contains TLR 2 or TLR 2 antibody as an active ingredient.COPYRIGHT KIPO 2012본 발명은 톨 유사 수용체 2를 약물타겟으로 이용한 신경변성 질환에 치료효과를 가지는 물질을 동정하는 방법 및 그 키트에 관한 것이다.