PROBLEM TO BE SOLVED: To provide a hypotensive agent containing a low molecular weight peptide, especially a peptide derived from globin protein degradation products as the effective component.SOLUTION: This hypotensive agent includes as effective ingredients at least one peptide selected from the group consisting of peptides comprising amino acid sequences shown in following (2) to (4), or globin protein degradation products containing at least one kind of these (2) Trp-Gly-Lys-Val-Asn (sequence number 2) (3) Trp-Gly-Lys-Val (sequence number 3) and (4) Trp-Gly-Lys (sequence number 4).COPYRIGHT: (C)2013,JPO&INPIT【課題】本発明は血圧降下剤を提供する。【解決手段】本発明の血圧降下剤は、下記(2)~(4)に示すアミノ酸配列からなるペプチドよりなる群から選択される少なくとも1種のペプチド、またはこれらのペプチドの少なくとも1種を含有するグロビン蛋白分解物を有効成分とする:(2) Trp-Gly-Lys-Val-Asn(配列番号2)(3) Trp-Gly-Lys-Val(配列番号3)(4) Trp-Gly-Lys(配列番号4)。【選択図】なし