KIM, SE-HO,SON, JI-YEON,LA, MUHN-HO,CHOI, SUNG-WON,SEO, MIN-HYO
申请号：
CA2748520
公开号：
CA2748520C
申请日:
2009.12.24
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Disclosed are an anionic drug-containing pharmaceutical compositioncomprising: ananionic drug as an active ingredient； a cationic lipid； and an amphiphilicblock copolymer,wherein the anionic drug forms a complex with the cationic lipid, and thecomplex is entrappedin the micelle structure of the amphiphilic block copolymer, and a method forpreparing thesame. The pharmaceutical composition may increase stability of the anionicdrug in blood or in abody fluid, and it may enable intracellular delivery to improve efficacy ofanionic drugs.
