IMMUNO-STIMULATING ACTIVITIES OF POLYSACCHARIDE FRACTIONS ISOLATED FROM CITRUS PEEL, PREPARING METHOD THEREOF AND HEALTH FUNCTIONAL FOOD COMPRISING THE THE SAME
BKBIO. CO., LTD.; LTD.;경기대학교 산학협력단;KYONGGI UNIVERSITY INDUSTRY & ACADEMIA COOPERATION FOUNDATION;주식회사 비케이바이오;BKBIO. CO.
发明人:
CHOI, HYUK JOON,최혁준,HAN, BOK KYUNG,한복경,PARK, SU BEOM,박수범,SHIN, KWANG SOON,신광순,PARK, HYE RYUNG,박혜령,LEE, MOON SU,김문수,CHOI, HYUK JOONKR,HAN, BOK KYUNGKR,PARK, SU BEOMKR,SHIN, KWANG SOONKR,PARK, HYE RYUNGKR,LEE, MOON SUKR
申请号：
KR1020130037651
公开号：
KR1020140121191A
申请日:
2013.04.05
申请国别(地区):
KR
年份:
2014
代理人:
摘要：
The present invention relates to a method for extracting immunostimulating polysaccharide having an immune boosting effect from by-products of citrus fruits such as a tangerine and a hallabong. The immunostimulating polysaccharide obtained by enzyme treatment according to the present invention has an excellent anticomplementary activity and superior capacities on proliferation of lymphocytes and stimulation of the production of macrophage cytokines (IL-6 and IL-12) compared to immunostimulating polysaccharide from citrus fruits obtained by hot water extraction, and a composition comprising the immunostimulating polysaccharide as an active ingredient can be used as an immune adjuvant.본 발명은 감귤, 한라봉 등의 감귤류 가공부산물로부터 면역증강 기능을 가지는 면역활성 다당체를 추출하는 방법에 관한 것으로, 본 발명에 따라 효소처리에 의해 획득된 감귤류 유래 면역활성 다당체는 항보체활성이 우수하고, 림프구 증식, 대식세포 사이토카인(IL-6 및 IL-12) 생산자극 능력이 열수추출에 의해 획득된 감귤류 유래 면역활성 다당체에 비하여 우수하며, 상기 면역활성 다당체를 유효성분으로 포함하는 조성물은 면역활성보조제로 적용이 가능하다.
