用於腫瘤適應徵及與ｍＴＯＲ／ＰＩ３Ｋ／ＡＫＴ／路徑相關之疾病之ｍＴＯＲ激酶抑制劑农业专利-农业专业知识服务系统

发明人:: PERRIN-NINKOVIC, SOPHIE,佩伦　尼柯芙克　苏菲,珮倫　尼柯芙克　蘇菲,HARRIS, ROY L.,哈瑞斯　洛伊Ｌ,SAPIENZA, JOHN,沙潘兹　约翰,沙潘茲　約翰,SHEVLIN, GRAZIELLA,契林　葛瑞兹拉,契林　葛瑞茲拉,PAPA, PATRICK,帕派　派翠克,LEE, BRANDEN,李　布兰登,李　布蘭登,PACKAR,佩伦尼柯芙克苏菲,珮倫尼柯芙克蘇菲,哈瑞斯洛伊L,沙潘兹约翰,沙潘茲約翰,契林葛瑞兹拉,契林葛瑞茲拉,帕派派翠克,李布兰登,李布蘭登

摘要：: Provided herein are Heteroaryl Compounds having the following structure:wherein R1-R4 are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions, comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.本文中所提供者為具有下列結構之雜芳基化合物：其中R1-R4均如本文定義，包含有效量之雜芳基化合物之組合物，及用於治療或預防癌症、炎性症狀、免疫學症狀、神經變性疾病、糖尿病、肥胖、神經病症、與老化有關聯之疾病或心血管症狀之方法，其包括對有需要之病患投予有效量之雜芳基化合物。