"heavy chain variable region polypeptide, anti-pd-11 antibodies, antigen binding fragments, compositions, nucleic acids, vector, host cell, anti-pd-11 antibody production process, articles of manufacture, enhancement method of t-cell function, method of treating a dysfunctional cell disorder and using a composition "
BRYAN IRVING,HEATHER MAECKER,HENRY CHIU,JEANNE CHEUNG,SANJEEV MARIATHASAN,SOPHIE M. LEHAR,YAN WU,IRVING BRYAN,MAECKER HEATHER,CHIU HENRY,CHEUNG JEANNE,MARIATHASAN SANJEEV,LEHAR SOPHIE M,WU YAN
申请号：
BRPI0917592
公开号：
BRPI0917592A2
申请日:
2009.12.08
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
The present application relates to anti-PD-L1 antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, including infection ( e.g ., acute and chronic) and tumor immunity.
