Peter Johannes Holst,Allan Randrup Thomsen,Jan Pravsgaard Christensen
申请号:
US14817631
公开号:
US20150368672A1
申请日:
2015.08.04
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to a vaccine comprising a nucleic acid construct such as a DNA construct especially a nucleic acid construct comprising sequences encoding invariant chain operatively linked to antigenic protein or peptide encoding sequences. The vaccine stimulates an immune response, especially an immune response in an MHC-I dependent, but CD4+ T-cell independent manner.