Alri PRETORIUS,Frederika Elizabeth FABER,Helena Cornelia STEYN,Junita LIEBENBERG,Mirinda VAN KLEEF,Nontobeko THEMA,Selaelo Ivy TSHILWANE
申请号：
US16472153
公开号：
US20190307871A1
申请日:
2017.12.20
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Nucleic acids include sequences encoding Ehrlichia ruminantium epitopes which induce a CD4 immune response, and sequences encoding Ehrlichia ruminantium epitopes which induce a CD8 immune response. Multi-epitope DNA vaccines include the nucleic acids and polypeptides are encoded by the nucleic acids. Methods of eliciting an immune response against heartwater disease in a subject make use of the nucleic acids, multi-epitope DNA vaccines and polypeptides.
