Substituted-3H-imidazo[4,5-c]pyridine and 1H-pyrrolo[2,3-c]pyridine series of novel Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) and Stimulator for Interferon Genes (STING) modulators as cancer immunotherapeutics

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专利权人:

Inc.;Stingray Therapeutics

发明人:

Hariprasad Vankayalapati,Sunil Sharma,Mohan Rao Kaadige,Alexis Weston,Trason Thode

申请号：

US16529693

公开号：

US20200039979A1

申请日:

2019.08.01

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Substituted -3H-imidazo[4,5-c]pyridine and 1H-pyrrolo[2,3-c]pyridine series of novel Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) and related compounds, which are useful as inhibitors of ENPP1； synthetic methods for making the compounds； pharmaceutical compositions comprising the compounds； and methods of using the compounds and compositions to treat disorders associated with dysfunction of the ENPP1.

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中国工程科技知识中心

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http://www.ckcest.cn/home/