Methods and systems related to detecting disease, such as oral cancer, in a patient, using a viewing scope to investigate a patients tissues. The systems and methods excite and detect fluorescence from the tissue. The fluorescence can then be evaluated, and the possibility of certain diseases such as cancer can be determined. The devices include an ambient light management system (ALMS, often referred to as a “vestibular device”) that manages background light in the health practitioners office. This device can be used with scope systems for fluorescence based detection of abnormal tissue.
