The present invention relates to a method for manufacturing fruit enzymes, capable of manufacturing enzymes in which various fruits containing abundant fiber and nourishment and sweet wormwood including an anticancer effect or an anti-aging effect are included in a granular type allowing a user to easily absorb the same and enabling beneficial bacterial making intestines healthy to be actively increased as see weed fusiforme powder containing lots of iron and calcium is added to allow a user to absorb and digest the sweet wormwood without a loss.COPYRIGHT KIPO 2014[Reference numerals] (AA) Start (BB) First step of washing, chopping, and preprocessing 20-30 weight of apple, 20-30 weight of pear, 5-15 weight of tangerine, 5-15 weight of pineapple, and 20-40 weight of artemisia annua (CC) Second step of squeezing fruits and artemisia annua preprocessed in the first step, separating it into pulp and juice, each putting in stainless containers, firstly fermenting it, and adding the same amount of sugar in the juice (DD) Third step of mixing 30-50 weight of juice firstly fermented in the second step with 3-7 weight of hijiki powder, 3-7 weight of kelp powder, 3-7 weight of vitamin leaves powder, 5-15 weight of pearl barley powder, and 40-50 weight of crushed barley grain, spraying yellow chrysanthemum virus, and secondly fermenting it in a fermenting chamber at 25-35°C for 18-24 hours (EE) Fourth step of adding lactic acid plant in the juice secondly fermented in the third step and thirdly fermenting it in the fermenting chamber at 35-37°C for 8-12 hours (FF) Fifth step of adding the juice fermented in the second step to the juice thirdly fermented in the fourth step, kneading it in a form of granules, and drying it at low temperatures (GG) End본 발명은 풍부한 섬유질, 영양분이 포함된 다양한 과일과 항암 및 노화억제효과를 갖는 개똥쑥이 포함된 효소를 섭취가 용이한 과립형태로 제조하되 개똥쑥의 손실 없는 소화흡수를 위해 철분 및 칼슘이 풍부한 톳 분말을 첨가되어 있어 장을 건강하게 하는 유익균이 활발하게 증식될 수 있도록 한 과일 효소의 제조방법에 관한 것이다.본 발명의 바람직한 일 실시예에 따른 과일 효소의 제조방법은 사과 20 내지 30