The present invention relates to multifunctional protein molecules comprising decorin and uses thereof. In particular, the present invention relates to multifunctional protein molecules comprising decorin and a targeting polypeptide such as an antibody and methods of their production and uses thereof.本發明係關於包含核心蛋白聚糖之多功能蛋白分子及其用途。具體而言,本發明係關於包含核心蛋白聚糖及例如抗體之靶向多肽之多功能蛋白分子以及其生產方法及其用途。