The present disclosure is directed to ophthalmic compositions and methods of making the compositions. The compositions include an active agent drug/cyclodextrin complex substantially dissolved in an aqueous eye drop vehicle. The ophthalmic composition is generally in the form of a microsuspension including an active agent complex having a diameter of less than about 100 µm.本揭示內容係關於眼用組成物及製造該等組成物之方法。該等組成物包括實質上溶於水性點眼劑媒劑中之活性劑藥物/環糊精複合物。該眼用組成物大體上呈微懸液形式,該微懸液包括具有小於約100 μm之直徑的活性劑複合物。