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Liquid formulations of long-acting interferon alpha conjugates
专利权人:
Dae Seong Im
发明人:
Dae Seong Im,Jae Min Lee,Jong Soo Lee,Sung Min Bae,Se Chang Kwon
申请号:
US13881976
公开号:
US09669105B2
申请日:
2011.10.26
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Disclosed is a liquid formulation in which a long-acting INFα conjugate that has improved in vivo duration and stability can be stored stably for a long period of time. It comprises a stabilizer comprising a buffer, a sugar alcohol, a non-ionic surfactant and an isotonic agent. Being free of human serum albumin and other potential factors harmful to the body, the liquid formulation is free of concerns about viral infections and guarantees excellent storage stability to long-acting INFα conjugates.
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