DELAVENNE EMILIE FLORA AURORE,SIMON DANIEL JEAN JACQUES,SOMMER MORTEN OTTO ALEXANDER,TOFT KEHLER RASMUS VENDLER
申请号:
IN201717007749
公开号:
IN201717007749A
申请日:
2017.03.06
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The invention relates to a halogenated salicylanilide selected from closantel rafoxanide oxyclozanide and niclosamide and derivatives thereof including salts hydrates esters and the like for use in the topical treatment or prevention of infections caused by Gram positive bacteria such as Staphylococcus in particular Staphylococcus aureus and Streptococcus in particular Streptococcus pyogenes. Gram positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.