A syringe assembly connectible to an injector (10) including a syringe interface (20) and a drive member (100) includes a syringe portion (100a) including a barrel section (110a) to contain fluid to be pressurized and an outlet (132a) in fluid connection with the barrel section. The syringe assembly also includes an adapter (200) formed separately from the syringe portion (100a) and including a plurality of sections (210,250). At least two sections of the plurality of sections are engageable to nonremovably connect the adapter to the syringe portion. In a number of embodiment, the adapter includes only two section the engage to nonremovably connect the adapter to the syringe portion. The adapter further includes a mounting mechanism adapted to be connected to the injector syringe interface. The adapter can also include a passage in operative connection with the barrel section after connection of the adapter to the syringe portion so that upon connection of the adapter with the syringe portion, the drive member can pass through the passage to impart motion to a plunger slidably positionable within the barrel section.