PROBLEM TO BE SOLVED: To provide a model animal suitable for developing means effective in preventing or treating lipodystrophy, and a screening system and method for an agent effective in preventing or treating lipodystrophy using the model animal.SOLUTION: This invention relates to a screening system for a substance effective in preventing and/or treating lipodystrophy, the system including nonhuman model animals with defects in Trib1 function.COPYRIGHT: (C)2014,JPO&INPIT【課題】脂肪萎縮症の予防又は治療に有効な手段の開発に有用なモデル動物、並びにそれを用いた脂肪萎縮症の予防又は治療に有効な薬剤のスクリーニングシステム及び方法を提供する。【解決手段】Trib1機能欠損非ヒトモデル動物を含む、脂肪萎縮症の予防及び/又は治療に有効な物質のスクリーニングシステム。【選択図】図1
