MOLECULAR PROBE PRECURSOR FOR IMAGING PANCREATIC ISLET AND USE THEREOF

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专利权人:

国立大学法人京都大学;KYOTO UNIV;アークレイ株式会社;ARKRAY INC

发明人:

INAGAKI NOBUYA,稲垣 暢也,SAJI HIDEO,佐治 英郎,TOYODA KENTARO,豊田 健太郎,KIMURA HIROYUKI,木村 寛之,HIRAO YOSHI,平尾 佳,NAGAGAWA KENJI,永川 健児

申请号：

JP2014052008

公开号：

JP2014144963A

申请日:

2014.03.14

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

PROBLEM TO BE SOLVED: To provide a molecular probe precursor for imaging pancreatic islets.SOLUTION: This invention provides polypeptides represented by the following formulae (1)-(6) and their related sequences, or polypeptides having homology with the polypeptides: *-DLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH(1), *-LSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH(2), *-SKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH(3), *-KQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH(4), *-DLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH(5), and *-LSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH(6)【課題】膵島イメージング用分子プローブ前駆体の提供。【解決手段】下記式(１)～(６)及びその関連配列で表されるポリペプチド又は前記ポリペプチドと相同性を有するポリペプチド。*-DLSKQMEEEAVRLFIEWLK*NGGPSSGAPPPS-NH2(1)、*-LSKQMEEEAVRLFIEWLK*NGGPSSGAPPPS-NH2(2)、*-SKQMEEEAVRLFIEWLK*NGGPSSGAPPPS-NH2(3)、*-KQMEEEAVRLFIEWLK*NGGPSSGAPPPS-NH2(4)、*-DLSK*QMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2(5)、*-LSK*QMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2(6)【選択図】図６

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中国工程科技知识中心

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