It describes the alfavirus vehicle, including nucleic acid sequences that encode new antigens produced from a target's tumor. It also describes the nucleons, cells and methods associated with the vehicle, including the use as a vaccine.Se describen vectores de alfavirus que incluyen secuencias de acidos nucleicos que codifican neoantigenos derivados de un tumor de un sujeto. Tambien se describen nucleotidos, celulas y metodos asociados a los vectores, incluido su uso como vacunas
