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Composé 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole
专利权人:
LTD.;OTSUKA PHARMACEUTICAL CO.
发明人:
申请号:
EP12193820.3
公开号:
EP2570418A2
申请日:
2003.10.10
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention provides a 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound represented by the following general formula:wherein R1 represents a hydrogen atom or C1-C6 alkyl group, n represents an integer of 0 to 6, R2 represents a group -OR3 or the like, and R3 represents a hydrogen atom, C1-C6 alkyl group or the like, or R1 and -(CH2)nR2 may bind to each other together with carbon atoms adjacent thereto through nitrogen atoms so as to form a spiro ring represented by the general formula (H):wherein R41 is hydrogen, C1-C6 alkyl group or the like. The present compound has an excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria.
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