Jim Fink,Lisa Molloy,Ronan MacLoughlin,Claire Elizabeth Lillis,Michael Joseph Casey,John Matthew Mullins,Kieran James Hyland,Joesph Martin Grehan,Niall Scott Smith
申请号：
US14743711
公开号：
US20160001019A1
申请日:
2015.06.18
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Embodiments provide aerosolization device for providing aerosolized medicament to user. The aerosolization device includes conduit, aerosol generator, fluid receiving chamber, restrictor within the conduit, and indicator mechanism. Conduit has an inner wall and a mouthpiece end for causing an inspiratory flow. Aerosol generator includes a vibratable mesh laterally offset from the inner wall. Fluid receiving chamber receives liquid medicament. At least a portion of chamber is tapered such that liquid medicament is directed onto vibratable mesh for aerosolization. Restrictor defines a plurality of apertures that provide increases in pressure differential that vary with inspiratory flow rate within conduit and provide relatively laminar flow downstream of restrictor. Indicator mechanism indicates a state of flow parameters relative to a predefined range. Aerosol generator is configured to aerosolize at least a portion of liquid medicament only when flow parameters of the inspiratory flow are within range.
