Disclosed is a reusable anorectal ligation device, which is gun-shaped as a whole and comprises a handle, and a ligation mechanism detachably connected to the handle, wherein the handle is internally provided with a shooting mechanism for shooting the ligation mechanism, and a suction mechanism; the ligation mechanism comprises an inner gun barrel (21), a pushing sleeve (22), and a suture-tightening assembly (23) for ligation of lesion tissue; the pushing sleeve (22) is provided on the inner gun barrel (21) and can generate displacement relative to the inner gun barrel (21); an anti-reset structure for preventing the pushing sleeve (22) from being reset after displacement is provided between the pushing sleeve (22) and the inner gun barrel (21); the suture-tightening assembly (23) is mounted on the pushing sleeve (22); the shooting mechanism comprises a shooting switch (31), a guiding and pushing block (32), and a ventilation pipe top seat (33); and the handle is further internally provided with an electric control apparatus (5) for controlling a negative pressure pump (42). The ligation device can prevent medical workers from reusing the ligation mechanism, which acts as a disposable consumable item, so that infection can be prevented, and the operation thereof is safe.L'invention concerne un dispositif de ligature anorectale réutilisable, qui est en forme de pistolet dans son ensemble et comprend une poignée, et un mécanisme de ligature relié de façon détachable à la poignée, la poignée étant pourvue intérieurement d'un mécanisme de tir pour tirer le mécanisme de ligature, et un mécanisme d'aspiration; le mécanisme de ligature comprend un canon de pistolet interne (21), un manchon de poussée (22), et un ensemble serrage de suture (23) pour la ligature de tissu de lésion; le manchon de poussée (22) est disposé sur le cylindre de pistolet interne (21) et peut générer un déplacement par rapport au cylindre de pistolet interne (21); une structure anti-réinitialisation