A flexible or rigid sheath guiding mechanism, comprises: a splitter (101), a guiding sleeve tube (102), a flexible sheath (103), a rigid sheath (104) and a handle (105). A first end of the guiding sleeve tube (102) is mounted on an outlet of the splitter (101), the guiding sleeve tube (102) and provided coaxially with the outlet of the splitter (101). A second end of the guiding sleeve tube is inserted in the rigid sheath (104). The guiding sleeve tube (102) fits the rigid sheath (104). The handle (105) comprises a handle head (106) and a handle sleeve (107) which are fitted with each other. The splitter (101) is mounted in the handle head (106). The rigid sheath (104) is mounted on the handle sleeve (107). The flexible sheath (103) goes through the guiding sleeve tube (102) and the rigid sheath (104), and an end of the flexible sheath (103) is mounted on the outlet of the splitter (101). The flexible or rigid sheath guiding mechanism and an integrated all-around adjustable flexible-rigid endoscope thereof have characteristics of precise guiding, reliable positioning, simple structures, and convenient assembly.