A manipulator system for manipulating an internal body cavity includes a manipulator device having a motor driven actuating mechanism for moving at least two endoscopes capable of being introduced into the internal body cavity at respectively through an access opening, which endoscope devices respectively comprise an elongate shaft (3), said at least two endoscopes being movable respectively in a longitudinal direction and pivoting about a center of rotation (10) defined by the respective access opening, a control device (21, 71) having at least two control elements (22, 22 ', 22 ", 33, 72, 72', 72", 73) which respectively comprise a rod (23, 23 '), said at least two control elements (22, 22', 22 ", 33, 72, 72 ', 72", 73) being movable s respectively manually in the direction of a longitudinal axis and pivotable about a center of rotation (30), and a control means (75) which is adapted to detect a respective longitudinal displacement and a respective pivoting movement of said minus two control elements (22, 22 ', 22 ", 33, 72, 72', 72", 73) and to control the manipulator device (1) so that the endoscope device movements correspond to those of the at least two control members (22, 22 ', 22 ", 33, 72, 72', 72", 73), the control device (21, 71) being designed such that a relative position of the centers of rotation (30 ) control elements (22, 22 ', 22 ", 33, 72, 72', 72", 73) is adjustable. Figure 1 1/6 L’invention concerne un système de télémanipulateur servant à effectuer des manipulations dans une cavité corporelle interne, comportant un dispositif manipulateur doté d’un mécanisme d’actionnement entraîné par moteur pour déplacer au moins deux dispositifs endoscopes pouvant être introduits dans la cavité corporelle interne à travers respectivement une ouverture d’accès, lesquels dispositifs endoscopes comprennent respectivement une tige allongée (3), lesdits au moins deux dispositifs endoscopes pouvant être déplacés respectivement dans une direction longitudinal