PROLYL HYDROXYLASE INHIBITORS

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专利权人:

AERPIO THERAPEUTICS INC.

发明人:

GARDNER, JOSEPH H.,SHALWITZ, ROBERT

申请号：

MYPI 2012001217

公开号：

MY163511A

申请日:

2010.11.05

申请国别(地区):

MY

年份:

2017

代理人:

摘要：

DISCLOSED HEREIN ARE PROLYL HYDROXYLASE INHIBITORS THAT CAN STABILIZE HYPOXIA INDUCIBLE FACTOR-1 ALPHA (HIF-1α), AS WELL AS HYPOXIA INDUCIBLE FACTOR-2 (HIF-2). ALSO DISCLOSED HEREIN ARE PHARMACEUTICAL COMPOSITIONS COMPRISING ONE OR MORE OF THE DISCLOSED COMPOUNDS. YET FURTHER DISCLOSED ARE METHODS FOR STIMULATING THE CELLULAR IMMUNE RESPONSE IN A MAMMAL SUCH AS INCREASING PHAGOCYTOSIS, FOR EXAMPLE, PROLONGING THE LIFE OF PHAGOCYTES, INTER ALIA, KEROTYIOCYTES, AND NEUTROPHILS. AS SUCH THE DISCLOSED COMPOUNDS PROVIDE METHODS FOR TREATING DISEASES THAT RELATE TO THE BODY’S IMMUNE RESPONSE.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/