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PROLYL HYDROXYLASE INHIBITORS
专利权人:
Aerpio Therapeutics; Inc.
发明人:
Joseph H. Gardner,Robert Shalwitz
申请号:
US15366437
公开号:
US20170298019A1
申请日:
2016.12.01
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Disclosed herein are prolyl hydroxylase inhibitors that can stabilize hypoxia inducible factor-1 alpha (HIF-1α), as well as hypoxia inducible factor-2 (HIF-2). Also disclosed herein are pharmaceutical compositions comprising one or more of the disclosed compounds. Yet further disclosed are methods for stimulating the cellular immune response in a mammal such as increasing phagocytosis, for example, prolonging the life of phagocytes, inter alia, kerotyiocytes, neutrophils. As such the disclosed compounds provide methods for treating diseases that relate to the body's immune response.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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