The present invention relates to differential phase-contrast imaging, in particular to a structure of a diffraction grating, e.g. an analyzer grating and a phase grating, for X-ray differential phase-contrast imaging. In order to provide enhanced phase-gradient based image data, a diffraction grating (14, 15) for X-ray differential phase-contrast imaging, is provided with a first sub-area (23) comprising at least one portion (24) of a first grating structure (26) and at least one portion (28) of a second grating structure (30). The first grating structure comprises a plurality of bars (34) and gaps (36) with a first grating orientation GO1 (37), being arranged periodically, wherein the bars are arranged such that they change the phase and/or amplitude of an X-ray radiation and wherein the gaps are X-ray transparent. The second grating structure comprises a plurality of bars (40) and gaps (42) with a second grating orientation GO2 (44), being arranged periodically, wherein the bars are arranged such that they change the phase and/or amplitude of an X-ray radiation and wherein the gaps are X-ray transparent. The first grating orientation GO1 is different than the second grating orientation GO2. Thus, phase-gradient based image information can be acquired for different directions without the necessity to rotate or pivot any of the respective gratings between the acquisition steps, for example.Cette invention concerne l'imagerie différentielle en contraste de phase, en particulier, une structure de réseau de diffraction, par exemple, un réseau d'analyseur et un réseau de phase, pour la radiographie X différentielle en contraste de phase. Pour obtenir des données d'images à gradient de phase améliorées, un réseau de diffraction (14, 15) pour la radiographie X différentielle en contraste de phase comporte une première sous-zone (23) comprenant au moins une partie (24) d'une première structure de réseau (26) et au moins une partie (28) d'une seconde structure de réseau (30
