Methods for producing transgenic rodents having recombinant immunoglobulin loci

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专利权人:

Roland Buelow

发明人:

Roland Buelow

申请号：

US12701464

公开号：

US08907157B2

申请日:

2010.02.05

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The invention provides methods for the production of transgenic animals comprising a recombinant Ig locus, as well as transgenic antibodies derived therefrom. The methods involve meganuclease cleavage-stimulated homologous recombination in mammalian embryos.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/