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STABLE PRESSURIZED AEROSOL SOLUTION COMPOSITION OF GLYCOPYRRONIUM BROMIDE AND FORMOTEROL COMBINATION
专利权人:
CHIESI FARMACEUTICI S.P.A
发明人:
Sauro BONELLI,Diego Copelli,Massimiliano Dagli Alberi,Francesca Usberti,Enrico Zambelli
申请号:
US15196318
公开号:
US20160303045A1
申请日:
2016.06.29
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Aerosol solution compositions intended for use with a pressurized metered dose inhaler, comprising glycopyrronium bromide and formoterol, or a salt thereof or a solvate of said salt, optionally in combination with one or more additional active ingredients, and stabilized by a selected amount of a mineral acid, exhibit improved stability when contained in a can internally coated by a resin comprising a fluorinated ethylene propylene (FEP) polymer.
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