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STABLE PRESSURISED AEROSOL SOLUTION COMPOSITION OF GLYCOPYRRONIUM BROMIDE AND FORMOTEROL COMBINATION
专利权人:
CHIESI FARMACEUTICI S.p.A.
发明人:
Sauro BONELLI,Diego COPELLI,Massimiliano Dagli ALBERI,Francesca USBERTI,Enrico ZAMBELLI
申请号:
US14585533
公开号:
US20150182450A1
申请日:
2014.12.30
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Aerosol solution compositions intended for use with a pressurized metered dose inhaler, comprising glycopyrronium bromide and formoterol, or a salt thereof or a solvate of said salt, optionally in combination with one or more additional active ingredients, and stabilized by a selected amount of a mineral acid, exhibit improved stability when contained in a can internally coated by a resin comprising a fluorinated ethylene propylene (FEP) polymer.
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