PROBLEM TO BE SOLVED: To provide an enhancer having an activity capable of persistently enhancing an immune function even with administration of a small number of bacterial cells.SOLUTION: The present invention provides an immune function enhancer containing the bacterial cells of Lactobacillus pentosus strain TUA4337L (Accession No. NITE BP-1479) or a treated material thereof as an active ingredient and the activity enhancer of natural killer cells (NK cells) containing the bacterial cells of Lactobacillus pentosus strain TUA4337L (Accession No. NITE BP-1479) or a treated material thereof as an active ingredient.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】少量の菌体数の投与であっても持続的に免疫機能を亢進し得る活性を有する亢進剤を提供すること。【解決手段】ラクトバチルス・ペントーサス TUA4337L株(受託番号NITE BP-1479)の菌体またはその処理物を有効成分とする、免疫機能亢進剤、ならびにラクトバチルス・ペントーサス TUA4337L株(受託番号NITE BP-1479)の菌体またはその処理物を有効成分とする、ナチュラルキラー細胞(NK細胞)の活性亢進剤。【選択図】なし