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ANTI-CTTLA-4 ANTIBODIES AND METHODS OF USE OF THE SAME
专利权人:
MEMORIAL SLOAN KETTERING CANCER CENTER;LUDWIG INSTITUTE FOR CANCER RESEARCH LTD;AGENUS INC.
发明人:
CORNELIA ANNE MUNDT,DAVID ADAM SAVITSKY,DAVID SCHAER,DENNIS JOHN UNDERWOOD,GERD RITTER,IGOR PROSCURSHIM,JEAN-MARIE CUILLEROT,JEDD DAVID WOLCHOK,MARC VAN DIJK,MARK ARTHUR FINDEIS,NICHOLAS STUART WILSON
申请号:
BR112019011651
公开号:
BR112019011651A2
申请日:
2017.12.07
申请国别(地区):
BR
年份:
2020
代理人:
摘要:
the present disclosure provides antibodies that specifically bind to ctla-4 (e.g., human ctla-4) and antagonize ctla-4 function. pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells to produce these antibodies, and methods of treating an individual using these antibodies are also provided.a presente revelação fornece anticorpos que especificamente se ligam a ctla-4 (por exemplo, ctla-4 humano) e antagonizam função de ctla-4. também são fornecidas composições farmacêuticas que compreendem esses anticorpos, ácidos nucleicos que codificam esses anticorpos, vetores de expressão e células hospedeiras para produzir esses anticorpos, e métodos de tratamento de um indivíduo com o uso desses anticorpos.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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