Memorial Sloan Kettering Cancer Center;Ludwig Institute for Cancer Research Ltd;Agenus Inc.
发明人:
Marc van Dijk,Cornelia Anne Mundt,Gerd Ritter,David Schaer,Jedd David Wolchok,Taha Merghoub,David Adam Savitsky,Nicholas Stuart Wilson
申请号：
US15166305
公开号：
US10144779B2
申请日:
2016.05.27
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The instant disclosure provides antibodies that specifically bind to human CTLA-4 and antagonize CTLA-4 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.
