Ok-Kyoung Kwon;Sei Ryang Oh;Hyeong Kyu Lee;Ha Young Jang;Kyung Seop Ahn;Doo-Young Kim;Ji Won Park;Jung Hee Kim
发明人:
Sei Ryang Oh,Kyung Seop Ahn,Hyeong Kyu Lee,Ha Young Jang,Ok-Kyoung Kwon,Jung Hee Kim,Ji Won Park,Doo-Young Kim
申请号：
US14122789
公开号：
US20140228427A1
申请日:
2012.05.24
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to a pharmaceutical composition for the prevention or treatment of asthma comprising Wogonin as an active ingredient. The Wogonin of the present invention is excellent not only in relieving airway hypersensitivity that causes asthma in vivo, in inhibiting reactive oxygen species generation in the airway, and in inhibiting the infiltration of inflammatory cells in the bronchus, but also in inhibiting the generation of IgE in serum and bronchoalveolar lavage fluid, and in inhibiting the expressions of Th2 cytokines in the lung. Therefore, the Wogonin of the present invention can be effectively used as a composition for the prevention, treatment, or improvement of asthma.
