Provided herein are novel fused pyrimidinone derivatives of Formula I and synthetic intermediates that are useful in preparing the compounds of formula (I). Further provided herein is a method for preparation of a compound of formula (I) or intermediates, a pharmaceutical composition comprising a compound of formula (I), and use of a compound of formula (I).本文所提供的為化學式I之新的稠合嘧啶酮衍生物及其對製備化學式(I)之化合物有用的合成中間產物。本文進一步提供的是化學式(I)之化合物或中間產物的製備方法、包含化學式(I)之化合物的藥學組成物,以及化學式(I)之化合物的用途。