A hot-melt extruded composition is disclosed that includes about 20-80% wt. of a plant-derived phenolic material about 20-85% wt. of one or more edible or bioerodible excipients about 0-40% wt. of a surface active material about 0-40% wt. of an oral absorption enhancer and about 0-10% wt. of one or more pharmaceutical or food grade additives. The composition has been hot-melt extruded at a temperature substantially below the melting point of the plant-derived phenolic material to produce a hot-melt extruded composition wherein substantial degradation of the plant-derived phenolic material has not occurred.