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HOT-MELT EXTRUDED COMPOSITIONS CONTAINING PLANT-DERIVED PHENOLIC MATERIALS AND PROCESSES FOR THE PREPARATION THEREOF
专利权人:
发明人:
申请号:
EP10749551.7
公开号:
EP2470157A1
申请日:
2010.08.24
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
A hot-melt extruded composition is disclosed that includes about 20-80% wt. of a plant-derived phenolic material about 20-85% wt. of one or more edible or bioerodible excipients about 0-40% wt. of a surface active material about 0-40% wt. of an oral absorption enhancer and about 0-10% wt. of one or more pharmaceutical or food grade additives. The composition has been hot-melt extruded at a temperature substantially below the melting point of the plant-derived phenolic material to produce a hot-melt extruded composition wherein substantial degradation of the plant-derived phenolic material has not occurred.
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