Universitätsmedizin der Johannes Gutenberg-Universität Mainz;Johannes Gutenberg-Universität Mainz
发明人:
申请号：
EP18163057.5
公开号：
EP3542814A1
申请日:
2018.03.21
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
The present invention relates to a compound comprising- a first polypeptide sequence comprising at least three different amino acid sequences selected from the group consisting of GFTFSDYW (SEQ ID NO: 1), IRLKSNNYAA (SEQ ID NO: 2) and TFGNSFAY (SEQ ID NO: 3),- a second polypeptide sequence comprising at least three different amino acid sequences selected from the group consisting of TGAVTTNNY (SEQ ID NO: 4), GTN (SEQ ID NO: 5) and ALWYSNHWV (SEQ ID NO: 6),or a variant of any one of said amino acid sequences of SEQ ID NO: 1 to SEQ ID NO: 6 having a different amino acid at one or more positions,wherein said compound or variant is capable of binding to tumour-associated Mucin-1 (TA-MUC1).
