#$%^&*AU2013100366A420130613.pdf#####ABSTRACT The invention relates to herbal compositions comprising an enriched Mahogany extract and at least one pharmaceutically acceptable additive, wherein the extract comprises an effective amount of saponins and tannins. In particular, the present invention relates to a 5 pharmaceutical or dietary supplement composition comprising: an effective amount of an enriched Mahogany species extract and at least one pharmaceutically acceptable additive said extract comprising at least 0.0001% w/w saponins and tannins and wherein said extract has the ability to inhibit at least one activity selected from the group consisting of COX-2 activity, Caspase 3 activity, 2,2-azino-bis(310 ethylbenzothiazoline-6-sulphonic acid) (ABTS) activity, AKTI1 activity and ERKI activity (GH Matters) P92696.AU 4194325_1 (GHMafe.s) P92696.AJ0 O -n 0 o o0 N tim oC ( --I Q ~ -- O OC 0 N 0 ou n N timo OO OO :, Q Q Q N 0 S o@o 0 1 tC A0 0 SCO C> C CO C Q Q fl fl T N)l ~ ~ C x F zF e Fom ~~~~ ~ F F )0 tQ to ~mm coao U U d
