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CARTILAGE-HOMING PEPTIDE CONJUGATES AND METHODS OF USE THEREOF
专利权人:
INC.;BLAZE BIOSCIENCE
发明人:
Julia E. Novak,Natalie Winblade Naim,Dennis M. Miller,Scott Presnell,Claudia Jochheim,Mark Stroud
申请号:
US16492914
公开号:
US20200069812A1
申请日:
2018.03.16
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Peptides that home, target, migrate to, are directed to, are retained by, or accumulate in and/or bind to the cartilage or kidney of a subject are disclosed. Pharmaceutical compositions and uses for peptides or peptide-active agent complexes comprising such peptides are also disclosed. Such compositions can be formulated for targeted delivery of an active agent to a target region, tissue, structure or cell in the cartilage. Targeted compositions of the disclosure can deliver peptide or peptide-active agent complexes to target regions, tissues, structures, or cells targeted by the peptide.
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