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RENAL-HOMING PEPTIDE CONJUGATES AND METHODS OF USE THEREOF
专利权人:
BLAZE BIOSCIENCE; INC.
发明人:
Julia E. Novak,Natalie Winblade Narin,Dennis M. Miller
申请号:
US16621173
公开号:
US20200222549A1
申请日:
2018.06.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Peptides that home, target, migrate to, are directed to, are retained by, or accumulate in and/or bind to the kidney of a subject are disclosed. Pharmaceutical compositions and uses for peptides or peptide-active agent complexes comprising such peptide-active agent conjugates are also disclosed. Such compositions can be formulated for targeted delivery of an active agent to a target region, tissue, structure or cell in the kidney. Targeted compositions of the disclosure can deliver peptide or peptide-active agent complexes to targe regions, tissues, structures, or cells targeted by the peptide.
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