POSTECH ACADEMY-INDUSTRY FOUNDATION;INSTITUTE FOR BASIC SCIENCE
发明人:
SURH, CHARLES D.,LEE, JUN-YOUNG
申请号：
CA3064534
公开号：
CA3064534A1
申请日:
2018.05.25
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention relates to an antibody that binds to human interleukin-2 (hIL-2), and more particularly to an anti-hIL-2 antibody that binds specifically to a particular epitope of hIL-2, thereby inhibiting the binding of the hIL-2 to CD25. The anti-hIL-2 antibody of the present invention binds specifically to a particular epitope of hIL-2, thereby inhibiting the binding of the hIL-2 to CD25, thereby minimizing expansion of Treg cells. In addition, it stimulates the CD8+ T cells and NK cells that exhibit anti-tumor activity. Thus, the anti-hIL-2 antibody of the present invention is useful as a new anticancer therapeutic agent.
